[Common name] pymetrozine
[Structural formula]


                                  
[Chemical name] 4,5-2H-6-methyl-4(3-pyridine-methano-amino)-1,2,4-triadiazin-3-3(2H)-one
[Molecular formula] C₁₀H₁₁N₅O
[ Molecular weight] 217.2
[CAS no.] 123312-89-0
Physical and chemical properties]
[Appearance] colorless crystals
[Melting poin] 217oC
[Vapor pressure] : <4 x 10-3mPa (25oC)
[KOWlogP] -0.18
[Henry] <3.0 x 10-6Pa m3 mol-1 (calc.)
[S.g./density] 1.36 (20oC)
[Solubility]
a) In water: 0.29g/L (pH 6.5. 25oC)
b) In ethanol 2.25, hexane <0.001 (both in g/l. 20oC)
[Stability] stable in air, hydrolysis DT50 4.3 h (pH 1), 25d (pH 5)

Technical specifications]
Pymetrozine 92% tech. specification]
[Appearance] white to slightly yellow powder
[a.i. content] >=92%
[ Insoluble matter in acetone] <=1.0%
[Water] <=1.0%
[PH] 6 9
[Formulation types] WP; WG
[Analysis] determination by HPLC and UV detection

Applications]
[Action] insecticide selective against Homoptera, causing them to stop feeding.
[Uses]
a) Control of aphids and whitefly in vegetables, potatoes, ornamentals, cotton, deciduous and citrus fruit, tobacco, hops; both juvenile and adult stages are susceptible.Also for control of plant hoppers in rice.
 b) Application rates vary from 150g/ha on potatoes to 200 - 300g/ha on ornamentals,tobacco and cotton; 10 - 30g/hl on vegetables, fruit and hops.

Toxicology]
Oral: acute oral LD50 for rats 5820mg/kg
Skin and eyes: acute percutaneous LD50 for rats >2000mg/kg. Non-irritating to the skin and eyes (rabbits). Not a skin sensitiser to guinea pigs.
Inhalation: LC50 (4h) >1800mg/m3 air
NOEL: (2y) for rats 3.7mg/kg b.w. daily
ADI: 0.03mg/kg b.w.
Other: non-mutagenic in 5 assay tests, including the Ames test
Birds: acute oral LD50 for bobwhite quails, mallard ducks >2000mg/kg.LC50 for bobwhite quails (8d) >5200ppm
Fish: LC50 (96h) for rainbow trout and common carp >100mg/L
Daphnia: LC50 (48h) 87mg/L
Algae: LC50 (72h) for Scenedesmus subspicatus 47.1; LC50(5d) for Selenastrum capricornutum 21.7mg/L
Bees: oral LD50 (48h) >117 (Lig/bee; contact LD50 (48h)>200ig/bee
Worms: LC50 (14d) for Eisenia foetlda 1098mg/kg soil

[Packaging]   25kg/plastic woven bag or cardboard drum lined with plastic bag